Current studies
Here you will find details of some current research being carried out at North London NHS Foundation Trust.
To take part in any of the studies, or to find out more information please contact beh-tr.research@nhs.net or nlft.researchteam@nhs.net
Anxiety and Depression Research
CBT and the Neural Circuits of Anxiety — C&I only
To test whether specific neural circuitry changes, proposed on the basis of our neurocognitive model of anxiety, are a mechanism of action for CBT interventions.
Community Navigator Trial
Testing new ways to help people with treatment resistant depression who are also experiencing feelings of loneliness by increasing social inclusion in community. Closed for recruitment.
CONTACT-GAD - BEH only
To test the effectiveness of tailored ACT for reducing anxiety in older people with TR-GAD.
CoComp - C&I only
To identify potential neuro-cognitive mediators of psychotherapeutic interventions for depression. Closed for recruitment.
MATILDA — C&I only
To undertake a randomised feasibility study of the Matilda intervention to improve health, wellbeing and social networks of older adults with learning disability (LD). Closed for recruitment
PAX-D - C&I only
To evaluate the efficacy and mechanism of pramipexole (Parkinson’s medication) as add-on treatment for people with treatment resistant depression (TRD). Closed for recruitment.
Social Brain - C&I only
Looking at the social brain and decision-making skills in people seeking CBT for psychological difficulties.
To evaluate the efficacy and mechanism of pramipexole (Parkinson’s medication) as add-on treatment for people with treatment resistant depression (TRD). Closed for recruitment.
Social Brain - C&I only
Looking at the social brain and decision-making skills in people seeking CBT for psychological difficulties.
ADHD and Learning Disabilities Research
ART-CARMA - BEH only
The study of cardiometabolic risk factors and medication adherence in people with ADHD. Closed for recruitment.
PETAL
To develop a personalised treatment package for aggressive challenging behaviour in people with Learning Disabilities.
Bipolar Disorder Research
ASCEnD - C&I only
To examine the clinical and cost-effectiveness of Aripiprazole/sertraline combination in comparison with quetiapine for the treatment of bipolar depression.
Children, Adolescent and Young People Research
ERiC
To evaluate the clinical utility of Mentalization Based Treatment (MBT) for children with mixed emotional and behavioural difficulties.
Wellbeing While Waiting
To evaluate the effectiveness of social prescribing in CAMHS.
Dementia Research
SOCIAL — C&I only
Exploring impairment in theory of mind associated with decline in social functioning in Alzheimer's disease
Addictions Research
FORWARDS 2
To evaluate feasibility and determine if baclofen shows potential efficacy in facilitating detoxification from methadone in community-based opiate dependent participants
Routine Screening for Gambling-related Harm
To evaluate how feasible it is to introduce a short screening questionnaire for gambling-related harm in mental health and drug and alcohol services.
Intervention Research
ASsuRED
Improving outcomes in patients who self-harm by adapting and evaluating a brief Psychological Intervention in Emergency Departments.
DIAMONDS
To develop and test a self-management intervention that can specifically jelp people with Type II Diabetes and Serious Mental Illness
Finch - C&I only
To develop and test an intervention to prevent compulsory readmission and develop self-management skills among people who have been compulsorily detained under the Mental Health Act.
moreRESPECT
To trial an intervention designed to promote sexual health for people with severe mental illnesses and to assess its clinical and cost effectiveness.
ERiC - BEH only
To evaluate the clinical utility of Mentalization Based Treatment (MBT) for children with mixed emotional and behavioural difficulties.
Psychosis Research
ADEPP - C&I only
To establish the effectiveness and cost-effectiveness of an antidepressant medication (sertraline) for the prevention of a depressive episode following first episode psychosis (FEP).
CLEAR
To test the effectiveness of clozapine in treatment-resistant early psychosis in people aged 12 to under 25.
CNNP - BEH only
To understand the neurocognitive aspects of people with a psychotic disorder.
To understand the neurocognitive aspects of people with a psychotic disorder.
NIMPsy — C&I only
To understand neural ciruits and immunity in psychosis, and demonstrate a causal role for immune dysregulation in psychosis.
PIPP2
To establish the prevalence of neuronal cell surface antibodies in people with psychosis.
RADAR Follow-up
A long-term follow-up study investigating the effect of reduction and discontinuation of antipsychotic medication.
To establish the prevalence of neuronal cell surface antibodies in people with psychosis.
RADAR Follow-up
A long-term follow-up study investigating the effect of reduction and discontinuation of antipsychotic medication.
Genetic Testing Research
GLAD
To explore genetic predictors of depression and anxiety disorders.
Pharmacogentics in Mental Health - C&I only
To see if genetic testing could be useful for patients who are going to be given psychiatric drugs as treatment for their mental illness.
